SOUTH PORTLAND – About 45 workers at Fairchild Semiconductor will be laid off, the company announced.

Most of the laid-off workers were in manufacturing, said Fairchild spokeswoman Fran Harrison.

The company, which employed 1,682 workers at its South Portland plant before the layoffs, blamed the cuts on a slowdown in sales of personal computers and cellphones that use its chips.

The company saw its profits drop by half in the first quarter this year and announced last month that it planned to reduce its worldwide work force by 10 percent during the current quarter.

Fairchild, one of Maine’s biggest employers, has nearly 11,500 workers worldwide. The cuts, announced Thursday, come a month after National Semiconductor announced it would lay off 30 workers at its South Portland plant.