PORTLAND – An independent film by Tony Shalhoub, a University of Southern Maine graduate who stars on the TV series “Monk,” makes its Maine premiere Wednesday.

Shalhoub, who won a Golden Globe Award for playing an obsessive-compulsive detective on the USA network series, stars with his wife Brooke Adams in “Made-Up.”

The couple now has the daunting task of promoting the movie and distributing it on their own. They will be on hand to answer audience questions at 5 p.m. and 7:30 p.m. screenings at The Movies on Exchange in Portland.

Shalhoub, 49, said he and Adams decided to bring the film to Maine because of his long-term ties to the state. Shalhoub graduated from USM in 1977, began his professional acting career in Portland, and spoke at the USM graduation this May.

“Portland has played such a big part in my life and development, and I think Portland audiences are interested in independent films,” he said.

Shalhoub starred on the NBC sitcoms “Wings” and “Stark Raving Mad,” and his films include “Big Night,” “That Championship Season,” and “Men in Black.”

“Made-Up” is billed as a “mockumentary” in which the story is seen through the eyes of a character who’s making a documentary for her video class.