The elderly are the highest-risk population in the United States for suicide. But few suicide-prevention programs target them – a result, advocates say, of scarce funding and lack of concern for older Americans. Here is a look at some signs of depression, a top risk factor for suicide.

. Persistent sad, anxious or “empty” mood.

. Feelings of hopelessness, pessimism, guilt.

. Loss of interest in hobbies and other activities that were once enjoyed.

. Fatigue, restlessness, irritability.

. Difficulty concentrating, remembering, making decisions.

. Insomnia or oversleeping.

. Significant weight change.

. Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders and chronic pain.

. Thoughts of death.

Other factors that put elderly people at risk for suicide include:

. Previous suicide attempts or family history of suicide.

. Existing or past mental disorders.

. History of alcohol and substance abuse.

. Loss of personal, social or professional ties.

. Illness, isolation, access to lethal weapons.

Source: The Centers for Disease Control and Prevention, the National Institute for Mental Health.